虚拟导览
Comparative Studies of Palmatine with Metformin and Glimepiride on the Modulation of Insulin Dependent Signaling Pathway In Vitro, In Vivo & Ex Vivo
Associate Professor Dr Patrick Nwabueze Okechukwu & Abbirami Balachandran |Faculty of Applied Sciences
Congratulations to Associate Professor Dr Patrick Nwabueze Okechukwu and Ms Abbirami Balachandran for their recent publication entitled, “Comparative Studies of Palmatine with Metformin and Glimepiride on the Modulation of Insulin Dependent Signaling Pathway In Vitro, In Vivo & Ex Vivo” in Pharmaceuticals [JCR Impact Factor 2021 = 5.215, Q1 in Pharmacology and Pharmacy].
Using computational molecular docking and pharmacokinetics along with an experimental approach with three different models (in vitro, in vivo and ex vivo), the team discovered the antidiabetic effect of Palmatine in modulating the key proteins of the insulin signalling pathway, making it a potential therapeutic agent in the treatment and management of diabetes.
Link to article: https://doi.org/10.3390/ph15111317
